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Hardeep said, 8. ?Aloo Chaat [last weekend: No 54this weekend: No 96: In its fourth weekendthe film has collected 70 on 1 screen Total: 30737 [approx Rs 2265 lacs For all the latest Entertainment News download Indian Express App More Related NewsThe Karolinska Institute (KI) in Stockholm “has lost its confidence” in surgeon Paolo Macchiarini a senior researcher at the institute and will end its ties with him In a statement issued today KI said that it won’t renew Macchiarini’s contract after it expires on 30 November 2016 The move comes in the wake of a chilling three-part TV documentary about Macchiarini a former media darling who was cleared of scientific misconduct charges by KI vice-chancellor Anders Hamsten last summer Among other things The Experiments broadcast in January by Swedish public television channel SVT suggests that Macchiarini didn’t fully inform his patients about the risks of his pioneering trachea implants Most of the patients died including at least one—a woman treated in Krasnodar Russia—who was not seriously ill before the surgery In an email to Science KI spokesman Claes Keisu writes that Macchiarini has "overexploited Karolinska [Institute’s] brand in his work in Krasnodar His activities there have undermined KI’s reputation and damaged the public’s trust in KI" Discrepancies in Macchiarini’s CV contributed to the decision as well Keisu writes Macchiarini did not immediately respond to a request for comment on KI’s decision In an email to Science on Tuesday he wrote that the TV series “was a gross misrepresentation of fact” and that he couldn’t comment further at the moment The university’s statement says that between now and November the head of Macchiarini’s department will ensure that "Macchiarini uses his working hours to phase out the research he has conducted at KI" and that "the work of his research group is dismantled" The film has also raised questions about the way Hamsten and other administrators at KI Sweden’s most prestigious university and home of the selection committee for the Nobel Prize in Physiology or Medicine have handled the scandal Today the Institute’s Board decided to launch an independent review to be led by an experienced lawyer into KI’s 5-year relationship with Macchiarini Among the things the inquiry should address is whether any errors were made or laws were broken when Macchiarini was hired; whether misconduct charges against him were handled properly; and why given the controversy he was given a new 1-year contract as a senior researcher after his appointment as a visiting professor at KI ended in October 2015 “What has happened is having an impact on the reputation of the Institute” the board’s chairman Lars Leijonborg told Science earlier this week Politicians are worrying about fallout from the affair as well “I am concerned that it will affect the trust that we have from the public for Sweden as a prominent research nation and for the Karolinska Institute” Sweden’s minister for higher education and research Helene Hellmark Knutsson tells Science Macchiarini replaced missing or damaged windpipes with an artificial trachea made of a polymer scaffold “seeded” with the patients’ own stem cells which were supposed to grow into living tissue Between 2011 and 2014 he conducted three such transplants at Karolinska University Hospital four in cooperation with the Kuban State Medical University in Krasnodar as part of a formal clinical trial and one—on a toddler born without a trachea—in Illinois In 2014 colleagues at KI alleged that Macchiarini’s papers made his transplants seem more successful than they were omitting serious complications Two patients treated at Karolinska died and a third has been in intensive care since receiving a trachea in 2012 The Illinois patient also died as did three patients in Russia Bengt Gerdin a professor emeritus of surgery at Uppsala University in Sweden who investigated the charges at KI’s request concluded in May 2015 that differences between published papers and lab records constituted scientific misconduct But Hamsten rejected that conclusion in August based on additional material Macchiarini submitted later The documentary shows footage of a patient who says Macchiarini reassured him before the surgery that experiments had been done on pigs when in fact none had taken place It also follows the wrenching story of the first patient in Krasnodar A 33-year-old woman she was living with a tracheostomy that she said caused her pain but her condition was not life-threatening The film suggests that she wasn’t fully aware of the risks of the operation and that Macchiarini and his colleagues knew about problems with the implant before the surgery The patient’s first implant failed and she received a second one in 2013 She died in 2014 The fact that a relatively healthy patient underwent Macchiarini’s experimental procedure caused consternation in Sweden “We’ve seen footage in SVT’s documentary that is truly alarming and I empathise deeply with the patients and their relatives” Hamsten said in a KI statement issued last week “The information that has emerged in the documentaries on the ethical nature of these operations is new to Professor Hamsten” the university said The operations if they occurred as shown in the documentary would never have been approved at KI the university says However Macchiarini was open about his plan to include patients who didn’t have life-threatening conditions in the Krasnodar trial At KI “[w]e were allowed to do this type of transplantation only in extreme cases” he told Science in 2013 “The clinical study for the first time gives us a chance to include patients who are not in such critical shape” The KI’s investigation into Macchiarini’s CV was triggered by a story in Vanity Fair last month That article focused on Macchiarini’s past relationship with Benita Alexander an NBC News producer; among other things Alexander says Macchiarini convinced her that he had operated on several heads of state and that he would marry her in a ceremony officiated by Pope Francis in the presence of Barack Obama and Vladimir Putin The story also claimed Macchiarini had embellished his CV now with the benefit of such a wonderful building, For all the latest Lifestyle News.

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